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Functional genomics describes a set of conceptual approaches and associated laboratory techniques that rely on large-scale DNA sequence datasets to investigate the function of, and interactions  between, genes as well as their RNA/protein products. This Introduction to Functional Genomics will provide an overview of these techniques, including a) approaches to predicting protein function based on sequence analysis, b) large-scale genetic approaches to identifying novel genotype-phenotype associations, and c) transcriptomic, proteomic and metabolomic approaches that reveal gene functions by
measuring changes in abundance/modification of associated RNA transcripts, proteins and metabolites.

Assessment

This course does not involve any written exams. Students need to answer 5 assignment questions to complete the course, the answers will be in the form of written work in pdf or word. Students can write the answers in their own time. Each answer needs to be 200 words (1 Page). Once the answers are submitted, the tutor will check and assess the work.

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Course Credit: Indian institute of Technology Kanpur

Course Curriculum

lec1 Introduction to Functional Genomics 00:39:00
lec2 The Genomics Era 00:45:00
lec3 Epigenetics 00:29:00
lec4 Forward Genetics vs Reverse Genetics 00:28:00
lec5 Genome Editing Approaches (Part 1) 00:44:00
lec6 Genome Editing Approaches (Part 2) 00:43:00
lec7 Transcriptomics (Part 1) 00:33:00
lec8 Transcriptomics (Part 2) 00:23:00
lec9 Genome Sequence Databases 00:37:00
lec10 DNA Sequencing Methods (Part 1) 00:31:00
lec11 DNA Sequencing Methods (Part 2) 00:37:00
lec12 Applications of Next-Generation Sequencing (NGS) 00:35:00
lec13 Tutorial (Session 1) 00:30:00
lec14 Tutorial (Session 2) 00:38:00
lec15 Genomic Insight into Evolution 00:40:00
lec16 Genome sequence: Different Questions, Different Comparisons 00:44:00
lec17 Outcome of Comparative Genomics 00:45:00
lec18 Laboratory Session 1 00:32:00
lec19 Laboratory Session 2 00:27:00
Assessment
Submit Your Assignment 00:00:00
Certification 00:00:00

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