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The [course_title] course focuses on the fundamental concepts of Molecular, Cellular and Tissue Mechanics. You will explore the scaling laws and the methods of the continuum and statistical mechanics to biomechanical phenomena from molecular, cellular, tissue, and organ level. Prior knowledge of differential equations, molecular cell biology, statistical or classical thermodynamics will be helpful. The major concept includes Mechanics at the nanoscale, Mechanochemistry; Polymer mechanics, Muscle mechanics, electromechanical and physicochemical properties of tissues, Static and dynamic cell processes, Mechanobiology, and more.

Assessment

This course does not involve any written exams. Students need to answer 5 assignment questions to complete the course, the answers will be in the form of written work in pdf or word. Students can write the answers in their own time. Each answer need to be 200 words (1 Page). Once the answers are submitted, the tutor will check and assess the work.

Certification

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Course Credit: MIT

Course Curriculum

Length, Time, & Molecular-scale Forces in Biology 00:30:00
Single Molecule Mechanics 00:30:00
Energy Landscapes and Transition States 00:30:00
This resource may not render correctly in a screen reader.Quality Quantity Interactions 00:45:00
Kramers’ and Bell’s Models of Reversible Binding 00:30:00
Experimental Methods in Single Molecule Mechanics 00:35:00
Composition of Extracellular Matrix Constituents of Tissues; Relevance to Elastic (Time-independent) Behavior of Tissues 01:00:00
Elastic (Time-independent) Behavior of Tissues (cont.) 01:00:00
Elastic (Time-independent) Behavior of Tissues (cont.) 01:20:00
Finish Topics on Tissue Elasticity; Begin Viscoelasticity 00:30:00
Time-dependent Viscoelasticity of Tissues 00:35:00
Dynamic (Frequency-dependent) Viscoelasticity 00:30:00
Poroelastic (Time-dependent) Behavior of Tissues 00:30:00
Poroelastic (Frequency-dependent) Behavior of Tissues 00:35:00
Dynamic Nanomechanical Behavior of Extracellular Matrix Macromolecules 00:45:00
Time- and Frequency-dependent Behavior of Intracellular Networks 01:00:00
Cell Mechanics: Structure of the Cell 00:45:00
Visco / Poroelasticity, Large Amplitude Deformations 00:30:00
Microstructural Models of the Cytoskeleton 00:45:00
The Cell Membrane 00:15:00
Cell Motility and Mechanotransduction 00:45:00
The Physics of Cancer 01:20:00
Assessment
Submit Your Assignment 00:00:00
Certification 00:00:00

Course Reviews

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