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Clinical acid-base chemistry forms an integral part of the education of medical professionals, and is essential for the management of many patients in an acute care setting. Traditional approaches to this topic make use of over-simplified arguments. This course will teach you about Stewart’s model, how it uses a formal solution equilibrium approach which facilitates a clearer understanding of the process.


This course does not involve any written exams. Students need to answer 5 assignment questions to complete the course, the answers will be in the form of written work in pdf or word. Students can write the answers in their own time. Each answer needs to be 200 words (1 Page). Once the answers are submitted, the tutor will check and assess the work.


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Course Credit: University of the Witwatersrand

Course Curriculum

Module: 01
Introduction 00:02:00
The Basics of Aqueous Solutions 00:05:00
What’s wrong with the conventional approach? (Part1) 00:03:00
What’s wrong with the conventional approach? (Part 2) 00:03:00
Simultaneous Equations – The Very Basics 00:03:00
Dissolved Gases in Physiology 00:02:00
Module: 02
Acid-base behaviour of pure water including temperature effects on dissociation coefficient 00:08:00
Acid-base behaviour of pure water and strong ions 00:08:00
Acid-base behaviour of water, strong ions and a weak acid (protein) 00:05:00
Acid-base behaviour of water, strong ions, weak acid and carbon dioxide 00:07:00
Module: 03
Bicarbonate and respiratory effects 00:02:00
Review of the overall system of acid-base balance in terms of Stewart’s model 00:05:00
Clinical aspects of Stewart’s model – Part 1 00:03:00
Clinical aspects of Stewart’s model – Part 2 00:03:00
Stewart Calculator 00:01:00
Summary of the key concepts in acid-base chemistry including the nature of dependant and independent variables 00:03:00
Submit Your Assignment 00:00:00
Certification 00:00:00

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