The [course_title] course focuses on the fundamental concepts of Molecular, Cellular and Tissue Mechanics. You will explore the scaling laws and the methods of the continuum and statistical mechanics to biomechanical phenomena from molecular, cellular, tissue, and organ level. Prior knowledge of differential equations, molecular cell biology, statistical or classical thermodynamics will be helpful. The major concept includes Mechanics at the nanoscale, Mechanochemistry; Polymer mechanics, Muscle mechanics, electromechanical and physicochemical properties of tissues, Static and dynamic cell processes, Mechanobiology, and more.
Assessment
This course does not involve any written exams. Students need to answer 5 assignment questions to complete the course, the answers will be in the form of written work in pdf or word. Students can write the answers in their own time. Each answer need to be 200 words (1 Page). Once the answers are submitted, the tutor will check and assess the work.
Certification
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Course Credit: MIT
Course Curriculum
Length, Time, & Molecular-scale Forces in Biology | 00:30:00 | ||
Single Molecule Mechanics | 00:30:00 | ||
Energy Landscapes and Transition States | 00:30:00 | ||
This resource may not render correctly in a screen reader.Quality Quantity Interactions | 00:45:00 | ||
Kramers’ and Bell’s Models of Reversible Binding | 00:30:00 | ||
Experimental Methods in Single Molecule Mechanics | 00:35:00 | ||
Composition of Extracellular Matrix Constituents of Tissues; Relevance to Elastic (Time-independent) Behavior of Tissues | 01:00:00 | ||
Elastic (Time-independent) Behavior of Tissues (cont.) | 01:00:00 | ||
Elastic (Time-independent) Behavior of Tissues (cont.) | 01:20:00 | ||
Finish Topics on Tissue Elasticity; Begin Viscoelasticity | 00:30:00 | ||
Time-dependent Viscoelasticity of Tissues | 00:35:00 | ||
Dynamic (Frequency-dependent) Viscoelasticity | 00:30:00 | ||
Poroelastic (Time-dependent) Behavior of Tissues | 00:30:00 | ||
Poroelastic (Frequency-dependent) Behavior of Tissues | 00:35:00 | ||
Dynamic Nanomechanical Behavior of Extracellular Matrix Macromolecules | 00:45:00 | ||
Time- and Frequency-dependent Behavior of Intracellular Networks | 01:00:00 | ||
Cell Mechanics: Structure of the Cell | 00:45:00 | ||
Visco / Poroelasticity, Large Amplitude Deformations | 00:30:00 | ||
Microstructural Models of the Cytoskeleton | 00:45:00 | ||
The Cell Membrane | 00:15:00 | ||
Cell Motility and Mechanotransduction | 00:45:00 | ||
The Physics of Cancer | 01:20:00 | ||
Assessment | |||
Submit Your Assignment | 00:00:00 | ||
Certification | 00:00:00 |
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