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The principles of materials science and cell biology along with the design of medical implants, artificial organs, and matrices for tissue engineering are examined in the [course_title] course. The course focuses on the methods for biomaterials surface characterisation and analyses the protein adsorption on biomaterials. Major areas covered in the course are Molecular and cellular interactions with biomaterials, Mechanisms underlying wound healing and tissue remodelling, the design of implants, comparative analysis of analysis of intact, biodegradable, and bioreplaceable implants, etc.
Assessment
This course does not involve any written exams. Students need to answer 5 assignment questions to complete the course, the answers will be in the form of written work in pdf or word. Students can write the answers in their own time. Each answer needs to be 200 words (1 Page). Once the answers are submitted, the tutor will check and assess the work.
Certification
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Course Credit: MIT
Course Curriculum
| Tissue environment of the implanted biomaterial: unit cell processes | |||
| Survey of clinical cases of biomaterials-tissue interactions | 02:00:00 | ||
| Tissue structures and unit cell processes | 02:00:00 | ||
| Integrins and adhesion proteins | 02:00:00 | ||
| Unit cell processes comprising the healing response | 01:20:00 | ||
| Unit cell processes underlying tissue engineering | 00:45:00 | ||
| Structure and function of naturally occurring ECMs | 01:20:00 | ||
| ECM does not regenerate spontaneously | 00:45:00 | ||
| Cell-surface interactions | |||
| Analysis of surfaces of biomaterials and protein adsorption | 00:30:00 | ||
| Phenotype changes following adhesion on biomaterials | 00:45:00 | ||
| Structural determinants of biologically active materials | 01:20:00 | ||
| Methodology for cell-surface interactions | 01:00:00 | ||
| Cell-scaffold interactions during regeneration | 00:45:00 | ||
| Noncooperative cell-surface interactions | 01:00:00 | ||
| From randomness to cooperativity | 00:45:00 | ||
| In vivo and clinical case studies | |||
| Tissue response to implants; biocompatibility | 00:45:00 | ||
| Epithelialization (epidermal regeneration) and endothelialization of vascular prostheses | 02:00:00 | ||
| In vivo synthesis of skin | 01:20:00 | ||
| In vivo synthesis of peripheral nerve | 00:45:00 | ||
| Rules for synthesis of tissues and organs | 00:45:00 | ||
| Joints and dental tissues: prosthetic replacement | 02:30:00 | ||
| Implants for bone regeneration | 00:45:00 | ||
| Biomaterial applications in the heart and other organs | 01:00:00 | ||
| Assessment | |||
| Submit Your Assignment | 00:00:00 | ||
| Certification | 00:00:00 | ||
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